Transthoracic Echocardiographic Evaluation of the Cardiac Function During Transurethral Resection of Prostate in Elderly Patients

Yonsei University

Status: Terminated

Conditions: BPH

Study type: Observational

Funder types: Other

Identifiers

NCT02288780

4-2014-0734

Details and patient eligibility

About

Transurethral resection of the prostate (TURP) is a standard surgical treatment for benign prostatic hyperplasia (BPH). Non-conductive irrigation fluid is used to maintain good visibility of the operating field during resection of the prostate. Absorption of this hypotonic solution into the bloodstream can cause fluid overload and dilutional hyponatremia, resulting in adverse cardiovascular and central nervous system effects, transurethral resection (TUR) syndrome. BPH is common in elderly men above 60 years old. These aged people commonly have diastolic impairment by normal physiologic change without consistent symptom. This study aimed to evaluate the cardiac function focused mainly diastolic function during TURP with transthoracic echocardiography. Also, we will focus the effets of amount of irrgation fluid on left ventricular diastolic function in patients with pre-existing diastolic dysfunction.

Enrollment: 2 patients

Sex: Male

Ages: 65 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Above 65years of age
2. American Society of Anesthesiologists (ASA) Physical Status I, II, III.
3. undergoing transurethral resection of the prostate(TURP)"

Exclusion criteria

1. severe coagulopathy or bleeding disorder(platelet count<75000, PT INR >1.2)
2. short stature (under 150 cm)
3. underwent coronary artery bypass graft
4. contraindications of regional anesthesia "

Trial design

2 participants in 2 patient groups

Control

Description:

BPH patients with normal diastolic function

Diastolic dysfunction

Description:

BPH patients with preoperative diastolic dysfunction