Transversus Abdominis Plane Block and Inguinal Hernia Repair

Papacharalampous Panagiota

Status: Completed

Conditions: Postoperative Pain; Abdominal Wall Muscles; Inguinal Hernia; Regional Anesthesia

Treatments: Procedure: Transversus abdominis plane block

Study type: Interventional

Funder types: Other

Identifiers

NCT02030223

PAM-2345-1786

Details and patient eligibility

About

This prospective, randomized, double blinded, placebo-controlled study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided transversus abdominis plane block with ropivacaine 0,75 %, in patients undergoing unilateral inguinal hernia repair with a mesh under general anaesthesia, and how the efficiency of early postoperative analgesia achieved correlates with the risk of developing a chronic pain state, a not uncommon condition after this type of surgery.

Enrollment: 59 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

ASA I-III patients undergoing inguinal hernia repair with a mesh

age between 18 and 75 years old

ability to read and write greek

Exclusion criteria

• Inability to consent to the study
• BMI >40kg/m2
• Skin infection at the puncture site
• Contraindication to mono-amide local anaesthetics, paracetamol, NSAID's (parecoxib)
• Preoperative use of opioids or NSAID's for chronic pain conditions

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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59 participants in 2 patient groups, including a placebo group

Transversus abdominis plane block with 20 ml ropivacaine 0,75%

Active Comparator group

Description:

Transversus abdominis plane block with 20 ml ropivacaine 0,75%

Treatment:

Procedure: Transversus abdominis plane block

Transversus abdominis plane block with 20 ml saline

Placebo Comparator group

Description:

Transversus abdominis plane block with 20 ml saline

Treatment:

Procedure: Transversus abdominis plane block