Transversus Abdominis Plane Block for Laparoscopic Appendicectomy in Children

University Hospital Center (CHU)

Status: Unknown

Conditions: Laparoscopic Appendectomy

Treatments: Drug: Curare; Other: TAP block with Ropivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT02505841

9488

2014-A01431-46 (Registry Identifier)

Details and patient eligibility

About

The transversus abdominis plane (TAP) block is a regional anesthetic technique for post operative pain control after abdominal surgical procedures. Its effectiveness in children undergoing laparoscopic appendectomy has not been demonstrated. The investigators evaluate its analgesic efficacy over the first 24 post operative hours.

Enrollment: 240 estimated patients

Sex: All

Ages: 1 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient hospitalized in surgery and infantile anesthesia unit or admitted in emergencies for an laparoscopic appendectomy surgery.
• Patient whose general state corresponds to the classification of the American Society of Anesthesiologists (ASA) I to II
• Patient member in a national insurance scheme

Exclusion criteria

• Patient with drilled appendicitis or peritonitis
• Patient with a contraindication to local anesthesics
• Patient with a contraindication to TAP block
• Patient with allergies or known hypersensitivity to curare

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

240 participants in 3 patient groups

Group 1

Active Comparator group

Description:

Curare: Atracurium injection at 0.5 mg/kg

Treatment:

Drug: Curare

Group 2

Experimental group

Description:

TAP block and curare: Ultrasound-guided transversus abdominis plane block wih Ropivacaine injection 0.2% at 0.3 ml/kg then atracurium injection at 0.5 mg/kg

Treatment:

Other: TAP block with Ropivacaine

Drug: Curare

Group 3

Experimental group

Description:

TAP block: Ultrasound-guided transversus abdominis plane block wih Ropivacaine injection 0.2% at 0.3 ml/kg

Treatment:

Other: TAP block with Ropivacaine