Transversus Abdominis Plane Block From Abdominal Approach

United Christian Hospital

Status: Unknown

Conditions: Transversus Abdominis Plane Block From Abdominal Approach

Treatments: Procedure: Transversus abdominis plane block

Study type: Interventional

Funder types: Other

Identifiers

NCT01144273

KC/KE-10-0021/FR-3 (Other Identifier)

Protocol ver 1.1

Details and patient eligibility

About

Randomized double blind placebo controlled trial on transversus abdominus plane block approached from abdominal cavity, in patients undergoing total abdominal hysterectomy.

Full description

Potential advantages compared to percutaneous approach are decrease in risk of visceral injury as it is under direct visual and tactile guidance, ease of approach in obese patients, short theatre time for administration, easy to administer.

Enrollment: 50 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA physical status I-III
• Age 18 or above
• Scheduled to undergo TAH+/- salpingoophorectomy.
• Scheduled to receive general anaesthesia under standardized anaesthetic regime.
• Comprehends how to use intravenous patient controlled analgesia (IV PCA).
• Is willing to complete the postoperative assessment.
• Understands the nature and purpose of this study and the study procedures and has signed the informed consent form for this study to indicate this understanding.

Exclusion criteria

• Known allergy to drugs involved in this study
• Previously taking medications thought to result in opioid tolerance, or analgesics thought to interfere with subsequent opioid requirement.
• Undergoing any procedures in addition to TAH+/- salpingoophorectomy.
• With co-existing pathology resulting in persistent pain requiring analgesics.
• Wound incision extending to supra-umbilical level.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

---

50 participants in 2 patient groups, including a placebo group

0.5% Ropivacaine

Active Comparator group

Description:

group receiving TAP block (0.5% ropivacaine at TAP plane)

Treatment:

Procedure: Transversus abdominis plane block

normal saline

Placebo Comparator group

Description:

group receiving placebo (saline) at TAP plane

Treatment:

Procedure: Transversus abdominis plane block