Transversus Abdominis Plane Block Plus Quadratus Lumborum Block or Retrolaminar Block of Multiple Injections for Postoperative Analgesia Following Laparoscopic Colorectal Surgery

dong zhang

Status and phase: Not yet enrolling; Phase 4

Conditions: Quadratus Lumborum Block; Colorectal; Laparoscopic; Analgesia

Treatments: Procedure: Transversus abdominis plane block on the nonoperative side; Procedure: Quadratus lumborum block on the operative side; Procedure: Retrolaminar block on the operative side

Study type: Interventional

Funder types: Other

Identifiers

NCT05416866

GanSu Province

Details and patient eligibility

About

Our hypothesis was that transversus abdominis plane block plus retrolaminar block would reduce postoperative sufentanil consumption and provide superior analgesia compared with transversus abdominis plane block plus quadratus lumborum block for laparoscopic colorectal surgery.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists (ASA) physical status I-II class
• Colorectal cancer patients
• 18 and 80 years old
• Elective laparoscopic colorectal surgery

Exclusion criteria

• serious complications associated with other systems:
• severe cardiac insufficiency
• renal failure
• hepatic encephalopathy
• infection in the block injection area
• coagulopathy
• a known allergy to local anesthetics
• a previous history of tranquilizer or opioid abuse,
• body mass index (BMI) greater than 30 kg/m2 or less than 18 kg/m2,
• inability to cooperate with the assessment of visual analogue scale (VAS) pain scores
• refusal to participate in the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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100 participants in 2 patient groups

TR group

Experimental group

Description:

ultrasound-guided transversus abdominis plane block with 20 ml mixture 0.20% ropivacaine + dexamethasone 5 mg and retrolaminar block with 30-40 ml mixture 0.20% ropivacaine + dexamethasone 5 mg

Treatment:

Procedure: Retrolaminar block on the operative side

Procedure: Transversus abdominis plane block on the nonoperative side

TQ group

Experimental group

Description:

ultrasound-guided transversus abdominis plane block with 20 ml mixture 0.20% ropivacaine + dexamethasone 5 mg and quadratus lumborum block with 30 ml mixture 0.20% ropivacaine + dexamethasone 5 mg

Treatment:

Procedure: Transversus abdominis plane block on the nonoperative side

Procedure: Quadratus lumborum block on the operative side