Transversus Abdominis Plane Block Versus Quadratus Lumborum Block for Pain Management in Laparoscopic Appendectomy

Bakirkoy Dr. Sadi Konuk Training and Research Hospital

Status: Completed

Conditions: Surgery; Appendicitis Acute; Post Operative Pain

Treatments: Procedure: Transversus abdominis plane block; Procedure: Quadratus Lumborum Block

Study type: Interventional

Funder types: Other

Identifiers

NCT05310266

2020-35

Details and patient eligibility

About

Laparoscopic appendectomy causes postoperative pain. The primary objective of this prospective randomized controlled study is to compare the effect of ultrasound (US)-guided quadratus lumborum block (QLB) on 24-hour cumulative opioid requirements with transversus abdominis plane (TAP) block.

Full description

168 patients (ASA I-II-III) between 18 and 65 years of age, who were to undergo laparoscopic appendectomy, were randomized and divided into two groups. 32 patients were dropout for different reasons.(68 patients in each of the TAP block and QLB block groups). TAP block was performed for TAP group and QLB block was performed for QLB group. Postoperative analgesia was provided by intravenous tramadol hydrochloride using a patient-controlled analgesia device. 24-hour total tramadol hydrochloride consumption was primary outcome measure.Postoperative numeric rating scale values were the secondary outcome measure.

Enrollment: 168 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Ages of 18-65
• Patients who will undergo laparoscopic appendectomy
• ASA I-II-III patients

Exclusion criteria

• Clinically known local anesthetic allergy
• Morbid obesity (body mass index>40 kg m2)
• Clinically diagnosis of opioid, alcohol and substance dependence
• Clinically diagnosis of psychiatric disease
• Coagulopathy
• Patients with ASA IV-V

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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168 participants in 2 patient groups

Group TAP

Active Comparator group

Description:

The investigators performed transversus abdominis plane block to that patient group for postoperative analgesia

Treatment:

Procedure: Transversus abdominis plane block

Group QLB

Active Comparator group

Description:

The investigators performed quadratus lumborum block to that patient group for postoperative analgesia

Treatment:

Procedure: Quadratus Lumborum Block