Transversus Abdominis Plane Block vs Continuous Infiltration Wound Catheter for Analgesia After Caesarean Section (TAP-CAT)

Caen University Hospital

Status and phase: Completed; Phase 4

Conditions: Postoperative Pain

Treatments: Drug: CIC; Drug: USG-TAP block

Study type: Interventional

Funder types: Other

Identifiers

NCT03102515

2016-A00131-50

Details and patient eligibility

About

Analgesia following surgery associates different intra-venous or oral analgesic drugs and sometimes opioids. To reduce opioid consumption, loco-regional anaesthesia might be administered as a complement. In the specific context of caesarean sections, pain control is mandatory to enable the mother to take care of her offspring and shorten their hospital stay. This intervention is mainly performed under neuraxial anaesthesia (spinal or epidural), enabling the injection of morphine in the subdural or epidural space, as part of a multimodal analgesia regimen.

Studies have evaluated continuous wound infiltration catheters (CIC) and ultrasound-guided (UGD) transabdominis plane (TAP) block, and both techniques and both techniques reduce postoperative morphine consumption. Recent studies have compared the two techniques and found conflicting results. Furthermore, they did not consider caesarean section performed under epidural analgesia, with a different neuraxial injection site, neither did they compared pain after postoperative day 2.

Consequently, the aim of this study was to compare resting and standing pain up to postoperative day 3 after caesarean section performed under spinal or epidural anaesthesia and receiving either USG-TAP block or CIC. Baseline hypothesis was that the continuous infiltration provided a better analgesia at day 2.

Enrollment: 109 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Informed consent,
• Age>/=18 years,
• Caesarean section under spinal or epidural anaesthesia
• Technique surgical "Cohen Stark méthod".

Exclusion criteria

• Patient refusal,
• Patient under guardianship,
• Contraindication to one of the two techniques,
• Cesarean section under general anesthesia
• Allergies to local anesthetics
• Maternal instability

Trial design

109 participants in 2 patient groups

Spinal-anesthesia

Other group

Description:

Caesarean section performed under spinal anaesthesia and receiving either USG-TAP block or CIC

Treatment:

Drug: CIC

Drug: USG-TAP block

Epidural-anesthesia

Other group

Description:

Caesarean section performed under epidural anaesthesia and receiving either USG-TAP block or CIC

Treatment:

Drug: CIC

Drug: USG-TAP block