Transversus Abdominus Plane Block in Living Donor Hepatectomy (TAP Donor)

AlRefaey Kandeel

Status: Completed

Conditions: Living Donor Hepatectomy

Treatments: Drug: Dexmedetomedine; Device: surgically inserted Transversus abdominus plane catheter; Drug: Intravenous morphine; Drug: Bupevecaine

Study type: Interventional

Funder types: Other

Identifiers

NCT02708459

Abuelella TAP

Details and patient eligibility

About

Comparing different drugs used in Transversus abdominus plane analgesia after donor hepatectomy. Patients will be divided into three groups; control group, Bupivecaine group, and Dexmedetomedine group according to the used drug

Full description

Transversus abdominus plane block for postoperative analgesia after donor hpatectomy surgery using three different drugs control group, Bupivecaine group, and Dexmedetomedine group

Enrollment: 90 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all living hepatectomy donors in Mansoura liver transplantation program

Exclusion criteria

• refusal known sensetivity to used drugs

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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90 participants in 3 patient groups

Control

Active Comparator group

Description:

Control group where postoperative analgesia will be maintained by Morphine intravenous boluses (2 mg) if Visual analogue scale (VAS) scale more than 4.

Treatment:

Drug: Intravenous morphine

Bupevecaine group

Active Comparator group

Description:

Postoperative analgesia will be maintained by 20 ml Bupevecaine (0.25%) boluses in surgically inserted TAP catheter each 8 hours for 48 hours with rescue analgesia intravenous morphine (2mg) if VAS more than 4

Treatment:

Device: surgically inserted Transversus abdominus plane catheter

Drug: Bupevecaine

Drug: Intravenous morphine

Dex group

Active Comparator group

Description:

catheter will surgically inserted in Transversus abdominus plane (TAP) plane before wound closure Postoperative analgesia will be maintained by Dexmedetomedine 0.4 mg/kg plus Bupevecaine 0.25 20 ml boluses each 8 hours for 48 hours in surgically inserted TAP catheter with rescue analgesia intravenous morphine (2mg) if VAS more 4

Treatment:

Drug: Dexmedetomedine

Device: surgically inserted Transversus abdominus plane catheter

Drug: Bupevecaine

Drug: Intravenous morphine