Transversus Thoracic Muscle Plane Combined With Pectoral Nerves Block for Breast Cancer Surgery

University of Chinese Academy Sciences

Status: Completed

Conditions: Breast Cancer

Treatments: Procedure: the combination of transversus thoracic muscle plane and pectoral nerves blocks; Procedure: the pectoral nerves block only

Study type: Interventional

Funder types: Other

Identifiers

NCT05448638

IRB-2022-348

Details and patient eligibility

About

This is a prospective, randomized, controlled trial for evaluating the efficacy of addition of transversus thoracic muscle plane block to pectoral nerves block versus pectoral nerves block for quality of recovery scores in breast cancer surgery.

Full description

The pectoral nerves (PECS) block cannot block the most internal mammary region, whereas a transversus thoracic muscle plane (TTP) block can. The combination of PECS and TTP blocks may be suitable for breast cancer surgery. We studied patients undergoing breast cancer surgery to assess whether the combination of PECS and TTP blocks provides better postoperative recovery than PECS block alone.

Enrollment: 116 patients

Sex: Female

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• female, 18-80 years of age
• American Society of Anesthesiologists physical status I-III
• patients having elective unilateral breast cancer surgery

Exclusion criteria

• contraindication to nerve block
• inability to understand or communicate with research personnel
• chronic use of opioids or nonsteroidal anti-inflammatory drugs
• pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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116 participants in 2 patient groups

transversus thoracic muscle plane block+pectoral nerves block

Experimental group

Description:

the combination of transversus thoracic muscle plane and pectoral nerves blocks

Treatment:

Procedure: the combination of transversus thoracic muscle plane and pectoral nerves blocks

pectoral nerves block

Active Comparator group

Description:

the pectoral nerves block only

Treatment:

Procedure: the pectoral nerves block only