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Transversus Thoracic Plane Block for Perioperative Analgesia in Cardiac Surgery

S

Saint-Joseph University

Status

Not yet enrolling

Conditions

Cardiac Surgery
Transversus Thoracic Plane Block
Post Operative Pain

Treatments

Procedure: Transversus Thoracic Plane Block

Study type

Interventional

Funder types

Other

Identifiers

NCT06546722
CEHDF2392

Details and patient eligibility

About

The goal of this clinical trial is to learn if perioperative Transversus Thoracic Plane Block (TTPB) decrease perioperative pain after cardiac surgery. The main questions it aims to answer are:

  1. does Transversus Thoracic Plane Block decrease perioperative pain after cardiac surgery more than the standard analgesic treatment?
  2. Are the results different if the investigators perform Transversus Thoracic Plane Block before surgery or at the end of surgery?

Enrollment

150 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • All patients scheduled for cardiac surgery via sternotomy under cardiopulmonary bypass

Exclusion criteria

  • Previous cardiac surgery
  • Urgent surgery
  • Pregnant women
  • Allergy to local anesthetics
  • Opioid dependence
  • Low ejection fraction < 30%
  • Presence or onset of cognitive or neurological disorders preventing pain assessment
  • Infection at injection sites
  • Coagulopathy
  • Patients on dual antiplatelet therapy
  • Renal insufficiency with Glomerular filtration rate (GFR) < 30 mL/min
  • History of thoracic radiotherapy
  • History of mastectomy

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

150 participants in 3 patient groups

Placebo
No Intervention group
Description:
This group receives standard analgesic treatment and no Transversus Thoracic Plane Block is performed
Transversus Thoracic Plane Block pre
Active Comparator group
Description:
This group receives standard analgesic treatment and Transversus Thoracic Plane Block is performed before surgery
Treatment:
Procedure: Transversus Thoracic Plane Block
Transversus Thoracic Plane Block post
Active Comparator group
Description:
This group receives standard analgesic treatment and Transversus Thoracic Plane Block is performed at the end of surgery
Treatment:
Procedure: Transversus Thoracic Plane Block

Trial contacts and locations

1

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Central trial contact

Joanna Tohme, MD

Data sourced from clinicaltrials.gov

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