Trapeziectomy vs. Trapeziometacarpal Limited Excision for Thumb Base Osteoarthritis

Karolinska Institute

Status: Active, not recruiting

Conditions: Thumb Osteoarthritis

Treatments: Procedure: Trapeziectomy; Procedure: trapeziometacarpal limited excision

Study type: Interventional

Funder types: Other

Identifiers

NCT04210687

TEvsTLE

Details and patient eligibility

About

A randomized comparison between trapeziectomy and trapeziometacarpal limited excision for thumb base osteoarthritis in 90 patients.

Enrollment: 90 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Painful osteoarthritis in the thumb base and radiological arthritis (Eaton Littler class 2-3) and clinical signs of thumb base osteoarthritis (pain at palpation of the thumb base joint and pain during grinding test).
• Pain at rest.
• Conservative treatment >6 months (activity modification, splinting, painkillers or thumb base steroid or PRP injection)

Exclusion criteria

• Rheumatoid arthritis.
• Ongoing infection in the hand or wrist. -
• History of gout or pseudo gout.
• Inability to co-operate with the follow-up protocol (language difficulties, severe psychiatric disorder, cognitive impairment, drug addiction).
• Intra-articular injection in the affected joint within 6 months.
• Eaton Littler class 4 (STT joint involved).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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90 participants in 2 patient groups

Trapeziectomy

Active Comparator group

Description:

Standard simple trapeziectomy, no pins.

Treatment:

Procedure: Trapeziectomy

trapeziometacarpal limited excision

Active Comparator group

Description:

Trapeziometacarpal limited excision; Narrow pseudarthrosis of the trapeziometacarpal joint.

Treatment:

Procedure: trapeziometacarpal limited excision