Treating Alzheimer's and Dementia With D-ribose

Practitioners Alliance Network

Status: Terminated

Conditions: Alzheimers; Dementia

Treatments: Dietary Supplement: d-ribose

Study type: Interventional

Funder types: Other

Identifiers

NCT02260141

PAN- ALZ001

Details and patient eligibility

About

To study the effectiveness of d-ribose in treating Alzheimer's and Dementia

Full description

Clinical experience and the pathophysiology of Alzheimer's, including neuronal insulin resistance, suggests that ribose improves clinical outcomes. This study will add ribose 5 gm 3 X day for 8 weeks to monitor outcomes in a pilot study.

Enrollment: 3 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• A diagnosis of Alzheimer's and/or dementia with a Mini Mental Status Exam ( MMSE) score over 12 or being ambulatory and able to travel outside the home with assistance.
• Must have a caregiver living with them.

Exclusion criteria

• Overt and severe causes of secondary dementia such as metastatic brain cancers, or severe overt infectious encephalopathies or severe autoimmune illness.
• Also, severe life threatening illnesses which would make them unlikely to be alive after 6-12 months.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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3 participants in 1 patient group

Treatment with d-ribose

Experimental group

Description:

Treatment with ribose 5 gm TID

Treatment:

Dietary Supplement: d-ribose