Treating Opioid Misuse Via Mindfulness-Based Just-in-Time Adaptive Intervention (MORE-JITAI)

Utah System of Higher Education (USHE)

Status: Active, not recruiting

Conditions: Chronic Pain

Treatments: Behavioral: Supporive Psychotherapy; Behavioral: MORE+JITAI

Study type: Interventional

Funder types: Other

Identifiers

NCT04567043

00078615.2

Details and patient eligibility

About

This pilot RCT will examine the preliminary efficacy of a telehealth version of Mindfulness-Oriented Recovery Enhancement (MORE) enriched with a smartphone-based just-in-time adaptive intervention (JITAI) for patients with chronic pain on long-term opioid therapy.

Enrollment: 63 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Current chronic pain diagnosis determined by physician assessment (including but not limited to ICD-9 diagnoses 338.0, 338.21, 338.22, 338.28, 338.29, 338.4)
• Current use of prescription opioid agonist or mixed agonist-antagonist analgesics for >90 days
• Willingness to participate in study interventions and assessments

Exclusion criteria

• Prior experience with Mindfulness-Based Stress Reduction, Mindfulness-Based Cognitive Therapy, or Mindfulness-Based Relapse Prevention
• Active suicidality, schizophrenia, psychotic disorder
• Presence of clinically unstable systemic illness judged to interfere with treatment
• No access to internet (which will prevent telehealth-based treatment)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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63 participants in 2 patient groups

Mindfulness-Oriented Recovery Enhancement+JITAI

Experimental group

Description:

Participants will attend a telehealth Mindfulness-Oriented Recovery Enhancement (MORE) group plus mindfulness JITAI weekly for eight weeks.

Treatment:

Behavioral: MORE+JITAI

Supportive Psychotherapy

Active Comparator group

Description:

Participants will attend a telehealth supportive psychotherapy group weekly for eight weeks.

Treatment:

Behavioral: Supporive Psychotherapy