Treatment and Fate in Fistulizing Crohn's Disease in a Pediatric Population

Central Hospital, Nancy, France

Status: Active, not recruiting

Conditions: Crohn Disease

Treatments: Drug: Infliximab; Procedure: Stomy

Study type: Observational

Funder types: Other

Identifiers

NCT05759104

2022PI067

Details and patient eligibility

About

Crohn's disease is a inflammatory bowel disease evolving towards the destruction of the intestinal wall resulting in stenosing or perforating complications (fistulas, abscesses).

The treatment of perforating Crohn's disease is not codified.

Full description

The old dogmas leading to surgery after failure of medical treatment have recently been overturned, particularly since the advent of anti-TNFs.

Biotherapies now have a central place, including for complicated forms. Previous studies have already looked at the usefulness of anti-TNFs in stenosing forms, or concerning ano-perineal lesions, but what about digestive fistulas.

Indeed, data are scarce, especially in paediatrics.

Enrollment: 40 patients

Sex: All

Ages: 3 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Minor patients (aged 3 to 18).
• Diagnosed with Crohn's disease.
• fistulizing crohn's disease

Exclusion criteria

• perianal crohn disease