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Treatment Choices for Improving Adherence and Outcome

Weill Cornell Medicine (WCM) logo

Weill Cornell Medicine (WCM)

Status

Completed

Conditions

Major Depression

Treatments

Behavioral: interpersonal psychotherapy
Drug: escitalopram

Study type

Interventional

Funder types

Other
NIH

Identifiers

NCT00194948
K23MH069784 (U.S. NIH Grant/Contract)
DSIR 8K-RTSE

Details and patient eligibility

About

This study will determine the effectiveness of offering primary care patients their preferred treatment versus one that is less desirable in improving treatment adherence and outcome.

Full description

This study investigates whether offering primary care patients treatment that is congruent with their preferred first choice improves adherence and outcomes, in comparison to offering treatment that is not congruent with their preferred first choice. All subjects are offered a treatment with demonstrated efficacy, namely either the antidepressant medication escitalopram or Interpersonal Psychotherapy for 5 months. We hypothesize that patients who receive congruent treatment will be more likely to initiate treatment, adhere to treatment, and achieve depression remission.

Sex

All

Ages

21+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • age 21-99
  • English-speaking
  • DSM-IV criteria for major depression

Exclusion criteria

  • unable to give informed consent
  • MMSE<24
  • DSM-IV diagnosis of bipolar disorder, psychotic disorder, current alcohol or substance abuse
  • active suicide ideation
  • aphasia
  • acute or severe medical illness
  • currently receiving either antidepressant medication or psychotherapy

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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