Treatment for Borderline Personality Disorder

University of Iowa

Status: Completed

Conditions: Borderline Personality Disorder

Treatments: Behavioral: Treatment As Usual (TAU); Behavioral: Systems Training for Emotional Predictability and Problem Solving (STEPPS)

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00055315

200112066

DATR A2-AIR

R01MH063746 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study will expose patients to either a Systems Training for Emotional Predictability and Problem Solving (STEPPS) or treatment as usual (TAU) to determine the more effective therapy for treating borderline personality disorder.

Full description

Participants are randomly assigned to receive either Systems Training for Emotional Predictability and Problem Solving (STEPPS) or treatment as usual (TAU) for 20 weeks. STEPPS is a new cognitive behavioral treatment which involves skills training for emotion management and lifestyle behaviors as well as education for the affected individual's family members, friends, and professional caregivers. Participants are assessed at baseline and Weeks 4, 8, 12, 16, and 20. Interviews of patient's health care providers and family members and self-rating scales are used to assess patients. Follow-up assessments are made 1, 3, 6, 9, and 12 months after study completion. Participants must live within a reasonable driving distance of Iowa City, IA.

Enrollment: 383 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Borderline Personality Disorder

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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383 participants in 2 patient groups, including a placebo group

STEPPS

Active Comparator group

Description:

Patients with Borderline Personality Disorder. Each subject met DSM-IV criteria for BPD, confirmed through a clinical interview and a review of the patient's case notes

Treatment:

Behavioral: Systems Training for Emotional Predictability and Problem Solving (STEPPS)

Treatment as Usual

Placebo Comparator group

Description:

Patients with Borderline Personality Disorder. Each subject met DSM-IV criteria for BPD, confirmed through a clinical interview and a review of the patient's case notes. TAU for this BPD population includes medical management, group and individual therapy.

Treatment:

Behavioral: Treatment As Usual (TAU)