Treatment for Women With Post-Traumatic Stress Disorder Related to Childhood Abuse

NYU Langone Health

Status

Completed

Conditions

Stress Disorders, Post-Traumatic

Treatments

Behavioral: Psychotherapy treatment

Study type

Interventional

Funder types

Other

NIH

Identifiers

NCT00069381

DSIR 83-ATAS

R01MH062347 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study will compare one- and two-component treatments in women with post-traumatic stress disorder (PTSD).

Full description

PTSD is a debilitating and often chronic anxiety disorder with serious psychiatric comorbidity. The most common trauma associated with PTSD among women is childhood abuse. PTSD related to childhood abuse may cause problems with emotion regulation and interpersonal functioning. This study will address three domains of PTSD related to childhood abuse: emotion management problems, interpersonal problems, and PTSD symptoms.

Participants in this study will be randomly assigned to 16 sessions of one of three treatments: Skills Training for Affective and Interpersonal Regulation (STAIR), which focuses on helping individuals strengthen and build skills in managing feelings and improving interpersonal relationships; Modified Prolonged Exposure (MPE), which focuses on developing narratives of abuse history and completing an "emotional processing" of the trauma in a safe environment; and a combination of STAIR and MPE. Dropout rates and adverse effects will be measured.

Enrollment

144 patients

Sex

Female

Ages

22 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

DSM-IV criteria for Post-Traumatic Stress Disorder related to childhood physical and/or sexual abuse by a care-giver
At least one clear memory of the abuse
Willing to have all assessments tape recorded and sessions video taped
Willing to maintain any concurrent treatments for the duration of the study

Exclusion criteria