Treatment of Apogeotropic Horizontal Canal Benign Paroxysmal Positional Vertigo (BPPV-HC)

Chonbuk National University

Status and phase: Completed; Phase 3

Conditions: HC-BPPV

Treatments: Procedure: sham maneuver; Procedure: Gufoni maneuver; Procedure: Head-shaking maneuver

Study type: Interventional

Funder types: Other

Identifiers

NCT00810641

KONOS

Details and patient eligibility

About

The purpose of this study was to compare the immediate efficacies of each treatment maneuvers in treatment of apogeotropic horizontal canal benign paroxysmal positional vertigo (HC-BPPV).

Full description

A randomized prospective study of patients with HC-BPPV. Patients with apogeotropic type of HC-BPPV were randomized to one of each three treatment groups at their first clinic visit. These groups included the Gufoni maneuver, head-shaking maneuver, and sham group in apogeotropic HC-BPPV. Responsiveness of treatment maneuver was determined by positioning maneuver immediately after each treatment method based on resolves of vertigo and positional nystagmus.

Enrollment: 157 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• a history of brief episodes of positional vertigo,
• direction-changing horizontal nystagmus beating toward the uppermost (apogeotropic nystagmus) or undermost (geotropic nystagmus) ear in both the lateral head turning positions,
• no spontaneous nystagmus during upright sitting position, and
• absence of identifiable central nervous system disorders that could explain the positional vertigo and nystagmus.

Exclusion criteria

• central positional nystagmus with identifiable CNS lesions that could explain the positional nystagmus

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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157 participants in 3 patient groups

Gufoni maneuver

Active Comparator group

Description:

Gufoni maneuver for apogeotropic HC-BPPV

Treatment:

Procedure: Gufoni maneuver

Headshaking maneuver

Active Comparator group

Description:

headshaking maneuver for apogeotropic HC BPPV

Treatment:

Procedure: Head-shaking maneuver

sham maneuver

Sham Comparator group

Description:

sham maneuver for apogeotropic HC BPPV

Treatment:

Procedure: sham maneuver