Treatment of Epidemic Keratoconjunctivitis With 2% Povidone-iodine

Mahidol University

Status and phase: Completed; Phase 4

Conditions: Viral Conjunctivitis

Treatments: Drug: 2% povidone-iodine

Study type: Interventional

Funder types: Other

Identifiers

NCT01179412

EKC2004

Details and patient eligibility

About

The purpose of this study is to determine the outcomes of treating epidemic keratoconjunctivitis with 2% povidone-iodine.

Full description

The study design was a prospective interventional case series. Our institutional ethical committee approved the study protocol in April 2004. We performed this study between July 2004 and December 2009. During this period, there were 2 episodes of EKC epidemic. The first episode was in 2006 and the second in 2009.

Enrollment: 172 patients

Sex: All

Ages: 7+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who were diagnosed with EKC at the outpatient ophthalmic unit

Exclusion criteria

• children younger than six years
• women being pregnant or during lactation
• history of allergy to povidone-iodine
• prior ocular surgery
• contact lens usage and chronic eye diseases with current eye medications.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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172 participants in 1 patient group

2% povidone-iodine

Experimental group

Treatment:

Drug: 2% povidone-iodine

Drug: 2% povidone-iodine