Treatment of Extended Spectrum Betalactamase Producing Bacteria Causing Urinary Tract Infections in General Practice

University of Oslo

Status: Completed

Conditions: Urinary Tract Infections

Study type: Observational

Funder types: Other

Identifiers

NCT01531023

2011/2214-3

Details and patient eligibility

About

The prevalence of extended spectrum beta-lactamase (ESBL) producing bacteria found in urine sample cultures has been increasing over the past decades.

The study hypothesis is to assess the clinical and microbiological outcome of pivmecillinam treatment of ESBL producing E. coli and K. Pneumoni, as well as to observe the clinical and microbiological outcome of the same group of bacteria treated with other antiinfectious agents.

Samples are gathered in primary care setting.

Enrollment: 168 patients

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients were urinary sample taken in a primary care setting shows significant growth of ESBL producing E. coli.

Above age 16.

Exclusion criteria

• Sample from patients in hospital care or living in nursing home facilities. Inability to understand and sign information leaflet.

Trial design

168 participants in 2 patient groups

ESBL producing E. coli bacteria

Description:

Group of patients with identified ESBL producing E.coli in a urine sample taken in a primary care setting.

Non-ESBL E.coli urinary tract infection

Description:

E.coli bacteria found in the setting of a urinary tract infection in a primary care setting where ESBL producing bacteria are not found.