Treatment of Gingival Recessions with Connective Tissue or Concentrated Growth Factor Membrane Using Tunnel Technique

Bulent Ecevit University

Status: Completed

Conditions: Gingival Recession

Treatments: Procedure: Connective tissue graft; Other: Concentrated growth factor membrane; Procedure: Tunnel technique

Study type: Interventional

Funder types: Other

Identifiers

NCT04561947

2017-82-09/08

Details and patient eligibility

About

This randomized controlled clinical study aimed to evaluate the success of the combination of tunnel technique and concentrated growth factor membrane for root coverage in treating multiple gingival recessions and compare with the gold standard connective tissue graft.

Full description

The study included 108 defects in 40 patients with Miller Class I and II gingival recession. Gingival recession defects were randomly divided into two groups. Tunnel technique + connective tissue graft was applied to 20 patients in the control group (51 defects) and tunnel technique + concentrated growth factor membrane was applied to 20 patients in the test group (57 defects). The results at baseline and 6 months were evaluated for the following clinical parameters: Mean root coverage, complete root coverage, probing depth, clinical attachment level, gingival recession depth, gingival recession width, keratinized tissue width and gingival thickness.

Enrollment: 40 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age ≥18 years
• periodontally and systemically healthy
• presence of Miller I or II class gingival recession defect in at least two teeth on the buccal aspect of incisors, canine and premolar teeth (≥ 2 mm in depth)
• gingival thickness ≥ 0.8 mm 2 mm apical to the gingival margin
• presence of identifiable cementoenamel junction (CEJ) (step ≤1 mm at the CEJ level and/or presence of a root irregularity/abrasion with identifiable CEJ was accepted
• full-mouth plaque score (FMPS) ≤20%.

Exclusion criteria

• smoking
• contraindications for surgical periodontal treatment
• presence of recession defects associated caries, restoration and furcation problems
• use of systemic antibiotics for any reason in the last 3 months.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

TT+CTG

Active Comparator group

Description:

The combined connective tissue graft (CTG) with tunnel technique (TT)

Treatment:

Procedure: Tunnel technique

Procedure: Connective tissue graft

TT+CGF

Experimental group

Description:

The combined concentrated growth factor (CGF) membrane with tunnel technique (TT)

Treatment:

Procedure: Tunnel technique

Other: Concentrated growth factor membrane