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Treatment of Internal Inflammatory Root Resorption Using Injectable PRF Revascularization Technque

F

Fayoum University

Status

Completed

Conditions

Root Resorption

Treatments

Biological: injectable PRF

Study type

Interventional

Funder types

Other

Identifiers

NCT04410679
FayoumU

Details and patient eligibility

About

Currently Endodontics looks forward for regeneration rather than repair. Regenerative endodontic therapy was limited to pulp revascularization of necrotic pulp in immature teeth , followed by mature teeth. Recently pulp revascularization technique by induction of blood clot was applied in the treatment of inflammatory root resorption. So far, no clinical study for management of teeth with inflammatory internal root resorption by using injectable PRF revascularization has been described in the literature. Thus, this is the first clinical attempt to manage inflammatory root resorption in necrotic incisor teeth using injectable PRF regenerative approach.

Full description

13 teeth in a total of 10 patients with inflammatory root resorption will be treated using revascualrization technique, iPRF will be prepared and unjected in the canal after previous canal disinfection with calcium hydroxide for 2-4 weeks. cBCT will be taken preoperative and 12 month follow up period, also clinical and radiographic follow uo will be considered every 3 months for 1 year.

Enrollment

10 patients

Sex

All

Ages

13 to 30 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • patients 13-30 years old
  • no sex predilection
  • medically free
  • Suffering from internal inflammatory root resorption in permanent anterior mature teeth
  • associated with or without periapical radiolucency
  • no or grade I tooth mobility, and a pocket depth <3 mm

Exclusion criteria

  • old age
  • Medically medically compromised patients

Trial design

Primary purpose

Treatment

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

10 participants in 1 patient group

injectabl PRF for treatment of internal root resorption
Experimental group
Treatment:
Biological: injectable PRF

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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