Treatment of Moderate FMR During AVR

Fuwai Yunnan Cardiovascular Hospital

Status: Not yet enrolling

Conditions: Functional Mitral Regurgitation

Treatments: Procedure: mitral valve repair

Study type: Observational

Funder types: Other

Identifiers

NCT05566340

FZX2019-06-01 2022YFKY088

Details and patient eligibility

About

Debates exist on the treatment of moderate functional mitral regurgitation (FMR) in patients undergoing aortic valve replacement (AVR) for aortic valve disease. This study aims to evaluate the left ventricular function, which was evaluated through global longitudinal strain, after isolated AVR and AVR + mitral valve repair (MVr) in this group of patients.

Enrollment: 154 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients who received AVR (with or without concomitant MVr) from two center (Fuwai Yunnan Cardiovascular Hospital and Fuwai Hospital, Chinese Academy of Medical Sciences).
2. Age more than 18 years.

Exclusion criteria

1. Those with a history of rheumatic valvular disease or infective endocarditis.
2. Primary mitral valve lesions.
3. Patients receiving mitral valve replacement.
4. Patient who refuse to participate in this study, or cannot complete 6-month follow-up after surgery.
5. Age < 18 years.

Trial design

154 participants in 2 patient groups

isolated aortic valve replacement group

Description:

Isolated aortic valve replacement surgery.

Treatment:

Procedure: mitral valve repair

aortic valve replacement with mitral valve repair group

Description:

Aortic valve replacement with mitral valve repair

Treatment:

Procedure: mitral valve repair