Treatment of Nevus Flammeus With Alexandrite Laser

Bispebjerg Hospital

Status: Completed

Conditions: Nevus Flammeus

Treatments: Procedure: Alexandrite laser

Study type: Interventional

Funder types: Other

Identifiers

NCT01968681

H-4-2013-066

Details and patient eligibility

About

Nevus flammeus is a congenital vascular malformation. Nevus flammeus is traditionally treated with pulsed dye lasers (PDL); however, around 20 percent of patients are poor responders and do not get satisfactory results from pulsed dye laser treatments.

Small studies with alexandrite lasers indicate that this may be an alternative treatment for individuals with nevus flammeus. This study assesses the clinical effect and side effects of alexandrite laser treatment for nevus flammeus using different treatment settings.

Enrollment: 19 patients

Sex: All

Ages: 10+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 10 or more years of age
• Fitzpatrick Skin Type I-III
• Previously untreated or pulsed dye laser-insufficiently treated nevus flammeus
• Nevus flammeus size minimum 8 x 2 centimeter within one anatomical region
• Written and oral informed consent

Exclusion criteria

• Known light sensibility toward visible light
• Tendency to develop hypertrophic scars or keloids
• Fitzpatrick Skin Type IV-VI
• Individuals, that are obviously pigmented due to recent sun exposure or sun beds
• Treatment with systemic retinoids within 6 months
• Pregnancy and lactation
• Unwillingness to complete protocol

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind

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19 participants in 1 patient group

Alexandrite laser treatment

Experimental group

Treatment:

Procedure: Alexandrite laser