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Treatment of Panic Disorder Among Individuals Consulting Emergency Departments for Non Cardiac Chest Pain (MADONA)

U

Université du Québec a Montréal

Status

Unknown

Conditions

Mental Disorder
Panic Disorder
Anxiety Disorder

Treatments

Behavioral: Cognitive-Behavior Therapy for Panic Disorder
Behavioral: Brief cognitive-behavioral treatment for Panic Disorder
Drug: paroxetine

Study type

Interventional

Funder types

Other

Identifiers

NCT00736346
MOP 81128 (CIHR)

Details and patient eligibility

About

The purpose of this study is to assess the impact of three different treatment modalities on panic symptoms, quality of life and use of health services among individuals consulting an emergency department for non cardiac chest pain and having Panic Disorder.

Enrollment

204 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Aged 18 and over
  • Mastered oral and written French
  • Consulted an emergency department for chest pain with very low risk of coronary disease (normal ECG and blood tests)
  • Met criteria for Panic Disorder

Exclusion criteria

  • Chest pain with an obvious medical origin (obvious trauma or abnormal pulmonary x-rays)
  • Had received cognitive-behavior therapy for Panic Disorder in the last six months
  • Cognitive impairment preventing the completion of psychological assessment
  • Past or present psychotic episode, Bipolar Disorder, or organic mental disorder
  • Current Abuse or Dependence Disorder
  • If another Mental Disorder is present, its severity was equal or inferior to the severity of Panic Disorder
  • Current medical condition preventing the participant from receiving pharmacological of cognitive-behavior treatment

Trial design

Primary purpose

Treatment

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

204 participants in 4 patient groups

1
Active Comparator group
Treatment:
Behavioral: Brief cognitive-behavioral treatment for Panic Disorder
2
Active Comparator group
Treatment:
Behavioral: Cognitive-Behavior Therapy for Panic Disorder
3
Active Comparator group
Treatment:
Drug: paroxetine
4
No Intervention group

Trial contacts and locations

3

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Central trial contact

Geneviève Belleville, PhD; André Marchand, PhD

Data sourced from clinicaltrials.gov

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