Treatment of Patients With Skin Burns Using Keratinocytes and Skin Fibroblasts

Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus

Status and phase: Completed; Phase 2; Phase 1

Conditions: Burns

Treatments: Biological: Fibroblasts and keratinocytes

Study type: Interventional

Funder types: Other

Identifiers

NCT04485962

IBCE_Fibr(Burns)

Details and patient eligibility

About

Treatment of patients with burns of the skin of the 2nd degree using: autologous keratinocytes and skin fibroblasts mixed with collagen gel 7% (tissue equivalent of the skin)

Full description

Treatment of patients with burns of the skin of the 2nd degree by applying a wound covering with layer-by-layer cultured autologous keratinocytes and fibroblasts in collagen gel

Enrollment: 12 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• skin burns of the 2nd degree

Exclusion criteria

• acute and chronic infectious diseases: HIV, viral hepatitis, tuberculosis
• mental disorders
• pregnancy

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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12 participants in 1 patient group

Fibroblasts and keratinocytes treated patients

Experimental group

Description:

Fibroblasts and keratinocytes treated patients

Treatment:

Biological: Fibroblasts and keratinocytes