ClinicalTrials.Veeva

Menu

Treatment of Peri-implant Bone Dehiscence Using Autogenous Tooth Plate

K

Kafrelsheikh University

Status

Completed

Conditions

Periodontal Diseases
Implant Complication
Peri-Implantitis

Treatments

Procedure: autogenous demineralized tooth graft and plate
Procedure: duoteck membrane
Procedure: autogenous demineralized tooth graft

Study type

Interventional

Funder types

Other

Identifiers

NCT06313216
KFSIRB200-187

Details and patient eligibility

About

The current trial aim was to evaluate clinically and radiographically the changes around dental implants inserted immediately in maxillary anterior esthetic zone using a novel combination of autogenous demineralized tooth graft. with autogenous demineralized tooth plate and compared this approach to autogenous demineralized tooth graft.

The present study included 63 patients, aged 20 to 45, with teeth that needed to be extracted. After Kafrelsheikh University research ethics committee approval, patients were randomized into 3 groups: group I patients underwent immediate implantation with Duo-Teck membrane, while group II patients underwent the same procedure, but the dehisced bone defect was grafted by autogenous demineralized tooth graft. finally group III was grafted by combination of autogenous demineralized tooth graft. with autogenous demineralized tooth plate.

Full description

Patients with missing teeth face the prospect of tooth replacement either through the use of removable prostheses, fixed natural teeth-supported prostheses, or implant-supported prostheses. In many circumstances, implants are the alternative to fixed or removable prosthetic appliances.

One of the various indications of implant therapy is the replacement of periodontally hopeless teeth. The successful use of dental implants for more than 3 decades has been extensively documented for both conventional and immediate implant therapy.

The installation of implants in extraction sockets was advocated as a means to reduce the number of surgical procedures; to preserve the dimensions of the alveolar ridge; to reduce the interval between the removal of the tooth and the insertion of the implant supported restoration and furthermore, it may enhance osseointegration by taking advantage of the natural bone healing process around the implant.

A variety of regenerative techniques using combinations of bone grafts and barrier membranes have been suggested to promote bone regeneration in localized defects at implants placed into extraction sockets (Mayfield 1999). Bone substitutes were used to fill the marginal void between the implant and the bone, and barrier membranes were placed to protect the site during healing.

In the presence of fenestration or dehiscence defects, the potential for spontaneous bone formation at such defects is poor, so it is advised to use augmentation procedures for bone enhancement. Bone augmentation procedures are effective in promoting bone fill and defect resolution at implants placed in post-extraction sites, and are more successful with immediate and immediate-delayed placement than with conventional delayed placement.

The current trial aim was to evaluate clinically and radiographically the changes around dental implants inserted immediately in maxillary anterior esthetic zone using a novel combination of autogenous demineralized tooth graft. with autogenous demineralized tooth plate and compared this approach to autogenous demineralized tooth graft.

Enrollment

63 patients

Sex

All

Ages

20 to 40 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • above the age of 18years
  • presence of non-restorable maxillary anterior tooth
  • had intact socket walls following tooth extraction
  • the gingival biotype was thick.

Exclusion criteria

  • history of systemic condition
  • history of using bisphosphonates or other drugs that might impact bone turnover
  • a history of smoking during the previous five years,
  • a history of any acute infections at the surgical site,
  • teeth having root resorptions

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

63 participants in 3 patient groups

Immediate Implant Placement Using duoteck membrane
Experimental group
Description:
after insertion of immediate implant, the dehisced bone defect will be grafted Using duoteck membrane
Treatment:
Procedure: duoteck membrane
Immediate Implant Placement autogenous demineralized tooth graft
Experimental group
Description:
after insertion of immediate implant, the dehisced bone defect will be grafted Using autogenous demineralized tooth graft
Treatment:
Procedure: autogenous demineralized tooth graft
Immediate Implant Placement with autogenous demineralized tooth graft and tooth plate
Experimental group
Description:
after insertion of immediate implant, the dehisced bone defect will be grafted Using autogenous demineralized tooth graft and autogenous demineralized tooth plate
Treatment:
Procedure: autogenous demineralized tooth graft and plate

Trial contacts and locations

1

Loading...

Central trial contact

Dalia Rasheed Issa, PhD; Walid AH Elamrousy, PhD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems