Treatment of Postoperative Pain After Total Hip Arthroplasty Using Intravenous Lidocaine Infusion

Loma Linda University (LLU)

Status and phase: Withdrawn; Phase 2; Phase 1

Conditions: Postoperative Pain Management After Total Hip Arthroplasty

Treatments: Other: Normal Saline; Drug: Lidocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT01108562

57366

Details and patient eligibility

About

This study will focus on patients undergoing total hip arthroplasty and Loma Linda University Medical Center & East Campus. These patients will be randomized to receive a low dose lidocaine infusion or placebo, in addition to the patient controlled analgesia pump. These groups will be compared to one another statistically to determine which group shows the safest and most satisfying pain control.

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adult male or female undergoing a total hip arthroplasty Subject is American Society of Anesthesiologists physical status 1, 2, or 3 Subject has voluntarily signed and dated the informed consent document approved by the IRB Be English speaking

Exclusion criteria

• Age > 80 years old or younger than 18 years old Congestive heart failure Hepatic insufficiency Neurological disorders Psychiatric disorders Steroid treatment No history of atrial fibrillation Chronic pain disorder with opioid treatment

Trial design

0 participants in 2 patient groups, including a placebo group

Control Group

Placebo Comparator group

Description:

Patients will receive a Dilaudid PCA in combination with a placebo infusion of normal saline.

Treatment:

Other: Normal Saline

Lidocaine Group

Experimental group

Description:

Patients will be receive a Dilaudid PCA in combination with a continuous Lidocaine infusion.

Treatment:

Drug: Lidocaine