Treatment of Severe Male Infertility - Predictive Factors (Imaging) (TESE-MRI)

Turku University Hospital (TYKS)

Status: Completed

Conditions: Male Infertility

Treatments: Diagnostic Test: MRI

Study type: Observational

Funder types: Other

Identifiers

NCT02931721

TESE-MRI

Details and patient eligibility

About

Testes of men with non-obstructive azoospermia (NOA) are imaged using MRI to find potential differences depending on the outcome, ie. sperm recovery in consequent microdissection testicular sperm extraction (MD-TESE).

Full description

Sperm recovery rate in non-obstructive azoospermia (NOA) men is 43% in Turku University Hospital, depending on the diagnosis leading to NOA. To date, there are no known parameters known to differentiate between successful and unsuccessful sperm recovery.

MRI is performed on men prior to the operation, and the objective is to compare the functional parameters assessed by magnetic resonance imaging between the group of men with positive and the men with negative sperm recovery in testicular microdissection sperm extraction (MD-TESE).

Enrollment: 30 patients

Sex: Male

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• non obstructive azospermia

Exclusion criteria

• malignancy
• contraindication for fertility treatment

Trial design

30 participants in 3 patient groups

MRI Positive

Description:

Men with sperm found in MD-TESE

Treatment:

Diagnostic Test: MRI

MRI Negative

Description:

Men with no sperm found in MD-TESE

Treatment:

Diagnostic Test: MRI

Control group

Description:

No intervention, fertile

Treatment:

Diagnostic Test: MRI