Treatment of Sudden Deafness With Prednisone+Hyperbaric Oxygen and Prednisone+Somatosensory Stimulation

Dan Su

Status: Unknown

Conditions: Hyperbaric Oxygen; Hearing Loss, Sudden; Prednisone Acetate; Somatic Stimulus

Treatments: Combination Product: Drugs and Stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT04129983

Pssd

Details and patient eligibility

About

To study the effective treatment of sudden deafness by giving prednisone, hyperbaric oxygen and somatosensory stimulation to sudden deafness patients.

Full description

60 cases of sudden deafness within 2 months of 14-80 years old were randomly divided into two groups. They underwent hearing tests, magnetic resonance imaging of the head, and routine hospital admissions. One group was given prednisone for 1 mg / kg body weight × 7 days + somatosensory stimulation × 30 days, the other group was given prednisone for 1 mg / kg body weight × 7 days + hyperbaric oxygen × 15 days, and repeated electrical audiometry every week. One month and three months after the experiment, repeated audiometry.

Enrollment: 60 estimated patients

Sex: All

Ages: 14 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Sudden deafness
• History within 2 months
• Age 14-80

Exclusion criteria

• Neurological diseases (such as brain tumors)
• Patients with mental / mental illness undergoing treatment
• Pregnant women and patients with other untreatable diseases
• Finding the cause of sensorineural deafness
• Patients Not Suitable for Hyperbaric Oxygen
• A patient with dermatosis

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

Prednisone acetate + somatosensory stimulation

Experimental group

Description:

Prednisone acetate 1 mg/kg body weight \* 7 days and somatosensory stimulation 30 days were given to sudden deafness patients.

Treatment:

Combination Product: Drugs and Stimulation

Prednisone acetate + hyperbaric oxygen

Experimental group

Description:

Prednisone acetate 1mg / kg body weight \* 7 days and hyperbaric oxygen 15 days were given to sudden deafness patients.

Treatment:

Combination Product: Drugs and Stimulation