Treatment Outcome in Patients After eCPR

University Hospital Ostrava

Status: Completed

Conditions: Cardiac Arrest (CA)

Treatments: Other: Quality of Life (SF-36); Other: Hospital Anxiety and Depression (HADS); Other: Retrospective analysis of assigned treatment; Other: Quality of Life (EQ-5D)

Study type: Observational

Funder types: Other

Identifiers

NCT07031466

FNO-KARIM-eCPR

Details and patient eligibility

About

This study consists of two parts - retrospective and prospective. The aim of this study is to assess the quality of life in bio-psycho-social dimensions in patients after eCPR (extracorporeal cardiopulmonary resuscitation), in relation to their neurological outcome after the end of treatment and discharge from the Ostrava University Hospital (FNO). The study will focus on patients who underwent extracorporeal membrane oxygenation (ECMO) support after out-of-hospital cardiac arrest (OHCA) in the years 2022-2024.

Full description

Retrospective study Quantitative evaluation using data analysis from documentation. Patients on ECMO after OHCA in the period 1. 1. 2022 - 31. 12. 2024 will be evaluated based on data from the documentation. Analysis of data from the documentation of selected patients will be performed, evaluating demographic data, comorbidities, duration of ECMO support, mortality, Cerebral Performance Category (CPC) score 30 days after CPR.

Prospective study Quantitative assessment using validated questionnaire tools Patients connected to ECMO after OHCA in the period 1. 1. 2022 - 31. 12. 2024, in whom a CPC score >3 was detected after the 30th day from cardiac arrest and who were discharged from the FNO. As part of patient dispensary, these patients are electively invited to the PICS outpatient clinic in the FNO Ostrava. Individual interviews (filling out questionnaires) will be performed after obtaining informed consent in the Post-Intensive Care Syndrome (PICS) outpatient clinic at the University Hospital Ostrava, or telephone interviews conducted by the attending physician.

Enrollment: 74 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient who underwent eCPR after OHCA at University Hospital Ostrava
• Hospitalised in the period from 1. 1. 2022 to 31. 12. 2024
• Ability to undergo an interview personally or a family member able to provide information
• Signed informed consent

Exclusion criteria

• Language barrier
• Acute serious mental or somatic disease making the interview not feasible

Trial design

74 participants in 2 patient groups

Retrospective eCPR group

Description:

Retrospective analysis of eCPR patients

Treatment:

Other: Retrospective analysis of assigned treatment

Prospective eCPR group

Description:

Prospective analysis of eCPR patients

Treatment:

Other: Quality of Life (EQ-5D)

Other: Hospital Anxiety and Depression (HADS)

Other: Quality of Life (SF-36)