Treatment Outcome of Clear Aligner and Traditional Fixed Appliances in Four Premolar Extraction Cases

Damascus University

Status: Completed

Conditions: Malocclusion, Class I/II; Crowding, Tooth

Treatments: Device: Clear Aligners; Device: Traditional fixed appliances

Study type: Interventional

Funder types: Other

Identifiers

NCT07236775

UDDS-Ortho-6-2025

Details and patient eligibility

About

Patients with severe crowding requiring the extraction of four premolars will be enrolled in this study. The degree of apical root resorption associated with using the clear aligner technique compared with vestibular fixed appliances in the treatment of severe crowding malocclusion cases requiring the extraction of first premolars will be evaluated using cone beam computed tomography (CBCT) volumes.

There are two groups:

First group (Experimental): the patients in this group will be treated using clear aligners.

Second group (Control): the patients in this group will be treated using fixed appliances.

Full description

With the increasing number of young adults requesting esthetic orthodontic treatment, clear aligners have continued to gain widespread use, driven by greater consideration of esthetic aspects and oral health-related quality of life compared to traditional fixed orthodontic appliances. Recently, clear aligners have been used in more complex malocclusion cases that require premolar extraction. Teeth root resorption occurs due to physiological or pathological causes that lead to loss of tooth structure. Apical root resorption (ARR) is a common side effect of orthodontic treatment that requires careful investigation of its location and frequency.

Enrollment: 40 patients

Sex: All

Ages: 18 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients aged 18-25 years.
• Class I malocclusion with severe dental crowding.
• Tooth size-arch discrepancy more than 6 mm.
• No congenitally missing or extracted teeth (except for the wisdom teeth).
• No history of previous trauma to the maxillofacial region or surgical interventions.

Exclusion criteria

• Previous orthodontic treatment.
• Presence of previously occurred ARR.
• Patients with psychological abnormalities or systemic diseases.
• Patients with known allergies to latex or plastic materials.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Clear Aligners

Experimental group

Description:

Patients in this group will be treated using clear aligners.

Treatment:

Device: Clear Aligners

Fixed appliances

Active Comparator group

Description:

Patients in this group will be treated using ordinary fixed appliances.

Treatment:

Device: Traditional fixed appliances