Treatment Patterns Among Patients With Venous Thromboembolism in the United States

Pfizer

Status: Completed

Conditions: Venous Thromboembolism

Treatments: Drug: warfarin; Drug: apixaban

Study type: Observational

Funder types: Industry

Identifiers

NCT05795062

B0661190

Details and patient eligibility

About

The purpose of this study is to assess outpatient treatment patterns following hospitalization for venous thromboembolism (VTE). VTE is a condition that occurs when blood clot forms in the vein.

This is a retrospective study (assessments on events that have already occurred) of healthcare claims from databases. The study sponsors will assess healthcare claim records of patients treated with either apixaban or warfarin. Assessment includes treatment persistence, switch, and stopping therapy, along with recurrent VTE and bleeding.

Enrollment: 13,945 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• inpatient hospitalization with primary discharge diagnosis of venous thromboembolism (VTE) (this is the index hospitalization)
• treatment with apixaban or warfarin during the hospitalization
• at least 18 years of age

Exclusion criteria

• Hospitalization for VTE within 6 months prior to the index hospitalization
• Diagnosis of atrial fibrillation/flutter or procedure for mechanical heart valve in the 6 months prior to the index hospitalization
• Procedure for inferior vena cava filter or diagnosis of pregnancy during the study period
• Prior use of oral anticoagulants or parenteral anticoagulants

Trial design

13,945 participants in 2 patient groups

apixaban

Description:

Patients treated with apixaban

Treatment:

Drug: apixaban

warfarin

Description:

patients treated with warfarin

Treatment:

Drug: warfarin