Treatment Protocol and Long-Term Outcomes in Craniofacial Fibrous Dysplasia (CFD)

Chang Gung Medical Foundation

Status: Completed

Conditions: Craniofacial Fibrous Dysplasia

Treatments: Procedure: Craniofacial reconstruction

Study type: Observational

Funder types: Other

Identifiers

NCT06167122

202000158B0

Details and patient eligibility

About

Craniofacial fibrous dysplasia (CFD) is a nonneoplastic disease characterized by fibro-osseous lesions in the affected bones. Treatment is mainly surgical and is stratified based on four different anatomical zones. This study aimed to evaluate the long-term outcomes and refine the algorithm for CFD.

Full description

According to Chen et. al for the appropriate surgical management of FD the craniofacial skeleton can be divided into four zones according to the consideration of facial cosmesis, vital anatomical region and function preserving. The aim of the study was to evaluate the outcome of nearly 40 years long-term follow up cohort group and refine the algorithm of surgical intervention of FD under 4 zones classification.

Enrollment: 13 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Received CFD surgical intervention between 1972 and 2019
• Personal interviews: between late 2019 and 2020, covering a postoperative period of over 20 years
• All the surgery were performed by a senior surgeon (Yu-Ray Chen) at Chang Gung Craniofacial Center

Exclusion criteria

• Patients who underwent surgical treatment at other institutions during the follow-up period or those who did not return to the craniofacial outpatient department for follow-up and receive computed tomography scans between 2019 and 2020 will be excluded.

Trial design

13 participants in 1 patient group

Craniofacial fibrous dysplasia

Description:

Fibro-osseous lesions within the affected bones based on image, and surgical intervention based on 4 different anatomical zones.

Treatment:

Procedure: Craniofacial reconstruction