Treatment Response and Prognosis in Glioma Patients: Q Cell and Its Biological Characteristics

Nanfang Hospital, Southern Medical University

Status: Unknown

Conditions: Glioblastoma; Malignant Glioma

Study type: Observational

Funder types: Other

Identifiers

NCT02047058

NFGC-001-MCP

Details and patient eligibility

About

The purpose of this study is to determine whether Q cells separated from the glioma sample are determinants in treatment response and prognosis of glioma patients

Full description

The unique markers of Qcell were screened using the method of genomics and

proteomics, then these markers will be qualitatively and quantitatively evaluated in

glioblastoma patients by comparing their relationship with overrall

survival/progression-free survival and treatment response.

Enrollment: 240 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. >=18 years old
2. Primary Glioblastoma is newly diagnosed and confirmed histologically
3. Patient is expected to be treated with temozolomide and followed up routinely at the study site.
4. Willing to sign the informed consent

Exclusion criteria

1. Currently enrolled in any other clinical study
2. History of any other malignancies
3. Refusal to give consent
4. No available tumor tissue for IDH analysis.

Trial design

240 participants in 1 patient group

high-risk

Description:

high-risk is determined by the evaluation of the biomarkers of Q cell.