Treatment With Duloxetine for OCD Patients

Sheba Medical Center

Status: Withdrawn

Conditions: OCD

Treatments: Drug: Duloxetine

Study type: Interventional

Funder types: Other

Identifiers

NCT00399022

SHEBA-06-4360-JZ-CTIL

Details and patient eligibility

About

Testing the efficacy of the SNRI medication Duloxetine for treating OCD patients who did not respond to SSRI

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• OCD as main diagnosis according to DSM-IV
• Age 18 to 65
• Men and women
• YBOCS score is 18 or more, or 12 or more in case of only obsessions

Exclusion criteria

• Patients treated with Duloxetine, currently or in the past
• Patients having comorbid schizophrenia or psychotic disorder or bipolar disorder Patients with substance abuse disorder in the last 6 months Patients who were suicidal or did serious suicide attempt in the last year Pregnant or lactating women, or woman of childbearing potential, which is not using adequate contraception Patients with neurologic disturbance or disorder Patients with serious or imbalanced medical condition Patients with allergic response to SSRI or duloxetine Patients who started new treatment (CBT or pharmacology) in less than 3 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind