Treatment With Ziprasidone for Schizophrenia Patients With Obsessive Compulsive Disorder (OCD)

Sheba Medical Center

Status: Completed

Conditions: Obsessive Compulsive Disorder; Schizophrenia

Treatments: Drug: Ziprasidone

Study type: Interventional

Funder types: Other

Identifiers

NCT00229385

SHEBA-03-3061-JS-CTIL

Details and patient eligibility

About

Comparing schizophrenic patients with comorbid OCD and schizophrenic patients without OCD in response to Ziprasidone and in cognitive functioning as compared with OCD patients

Enrollment: 45 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of Schizophrenia and OCD for at least 6 months
• Minimum score of 14 on YBOCS
• Minimum score of 60 on PANSS
• Diagnosis of Schizophrenia without OC symptoms

Exclusion criteria

• Patients who are already being treated with ziprasidone
• Diagnosis of schizophreniform disorder
• Organic brain syndrome, mental retardation and pervasive developmental disorder
• Patients having any significantly cardiovascular illness or electrolyte imbalance

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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45 participants in 2 patient groups

1

Active Comparator group

Treatment:

Drug: Ziprasidone

2

Active Comparator group

Treatment:

Drug: Ziprasidone