Trendelenburg Maneuver Predicts Fluid Responsiveness in Patients With Extracorporeal Membrane Oxygenation (TEMPLE)

Fudan University

Status: Unknown

Conditions: Extracorporeal Membrane Oxygenation

Treatments: Diagnostic Test: Trendelenburg Maneuver

Study type: Interventional

Funder types: Other

Identifiers

NCT03553459

TEMPLE

Details and patient eligibility

About

The purpose of the study is to verify the efficacy of using trendelenburg maneuver to predict fluid responsiveness in patients with extracorporeal membrane oxygenation

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with ECMO and mechanical ventilator support
• hypotension (MAP<65mmHg)
• required volume expansion by clinical judgement of the intensivists

Exclusion criteria

• severe hypotension with high dose of vasopressors
• severe valve regurgitation
• cardiac arrhythmia

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

Trendelenburg Maneuver

Experimental group

Description:

Trendelenburg maneuver is performed to predict fluid responsiveness. Responders are defined by an increase in stroke volume over 15% after infusion of 500ml of crystalloid solution.

Treatment:

Diagnostic Test: Trendelenburg Maneuver