Trends of Morbidity and Mortality Among Thai HIV-infected and HIV-uninfected Patients: a Five-year Prospective Cohort Study (TNT-HIV)

Thai Red Cross AIDS Research Centre

Status: Completed

Conditions: Healthy; HIV Infection

Study type: Observational

Funder types: Other; NETWORK

Identifiers

NCT01634477

TNT-HIV 003

Details and patient eligibility

About

1. To describe the morbidity and clinical characteristics among HIV-infected patients and HIV-uninfected patients.
2. To identify the risk factors for the complication or morbidity among HIV-infected patients and HIV-uninfected patients.
3. To describe the mortality among HIV-infected patients and HIV-uninfected patients.
4. To identify the risk factors for the cause of death among HIV-infected and HIV-uninfected patients.

Full description

The information obtained from this study would be very important in planning future holistic care of HIV-infected patients in our institutes as well as in national policy. Results from the study could be used to develop proper long-term management guidelines for people living with HIV (PLHIV) in Thailand targeted at preventable conditions such as metabolic diseases and certain cancers.

Enrollment: 816 patients

Sex: All

Ages: 30+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

HIV-infected patients group

• HIV positive
• 30 years of age or older, both male and female
• Thai nationality
• Written research informed consent

HIV-uninfected patients group

• HIV un-infected
• 30 years of age or older, both male and female
• Thai nationality
• Written research informed consent

Exclusion criteria

HIV-infected patients group

• Systolic BP ≥ 130 or Diastolic BP ≥ 85mm Hg or on the treatment
• Fasting blood sugar > 126 mg/dl or on the treatment
• Proteinuria
• Creatinine > 1.5 mg/dl
• Recent hospitalization
• Patient who are having mental disease HIV-uninfected patients group
• Systolic BP ≥ 130 or Diastolic BP ≥ 85mm Hg or on the treatment
• Fasting blood sugar > 126 mg/dl or on the treatment
• Proteinuria
• Creatinine > 1.5 mg/dl
• Recent hospitalization
• Patient who are having mental disease

Trial design

816 participants in 2 patient groups

HIV-infected patients group

Description:

HIV positive

HIV-uninfected patients group

Description:

HIV negative