Trial of Effect of High-frequency Transcranial Magnetic Stimulation in the Management of Borderline Personality Disorder

Tehran University of Medical Sciences

Status: Unknown

Conditions: Borderline Personality Disorder

Treatments: Device: rTMS; Device: sham rTMS

Study type: Interventional

Funder types: Other

Identifiers

NCT01602497

90-01-30-13200

Details and patient eligibility

About

This study is going to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on Borderline Personality Disorder patients symptoms.

Full description

There is a great body of literature about the positive effects of rTMS therapy on various psychiatric disorders. In this study we are going to evaluate the effects of high-frequency rTMS over the left dorsolateral prefrontal cortex (DLPFC)region in borderline personality disorder (BPD) patients. patients will be assessed by subjective measures for BPD.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinically diagnosed borderline personality disorder according to DSM IV.

Exclusion criteria

• Epilepsy
• Any metal device
• Psychotic disorders
• Bipolar mood disorder type 1

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups, including a placebo group

rTMS intervention group

Active Comparator group

Description:

The rTMS intervention group undergo ten session of real TMS therapy.

Treatment:

Device: rTMS

Sham group

Placebo Comparator group

Description:

Patients will undergo ten session of sham rTMS.

Treatment:

Device: sham rTMS