Trial of Rifaximin in the Treatment of Tropical Enteropathy

The Washington University

Status: Completed

Conditions: Tropical Enteropathy

Treatments: Drug: Rifaximin; Drug: Placebo

Study type: Interventional

Funder types: Other; Other U.S. Federal agency

Identifiers

NCT00858988

MJM-rifaximin

Details and patient eligibility

About

The purpose of this study is to determine whether rifaximin is effective in the treatment of tropical enteropathy in a population of African children at high risk for this disease.

Enrollment: 147 patients

Sex: All

Ages: 3 to 5 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• live in single village

Exclusion criteria

• acutely malnourished
• acutely ill
• chronic disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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147 participants in 2 patient groups, including a placebo group

Rifaximin

Experimental group

Treatment:

Drug: Rifaximin

Placebo

Placebo Comparator group

Treatment:

Drug: Placebo