Trial to Evaluate an Optimization Procedure of Alveolar Recruitment During Transport Performed by Nurse Anesthetists in Intensive Care (ESCORTE)

University Hospital Center (CHU)

Status: Completed

Conditions: Respiratory Complication

Treatments: Procedure: Clamping of the ventilator endotracheal tube

Study type: Interventional

Funder types: Other

Identifiers

NCT04159220

RECHMPL19_0070

Details and patient eligibility

About

Intra hospital transport of ICU patients is still at high risk of respiratory complications.We propose to determine if endotracheal tube clamping prior to disconnect ventilator allows to avoid oxygenation decrease.

Full description

Changing respiratory support and multiples endotracheal tube disconnections may induce a loss of PEEP and finally lead to alveolar derecruitment. This study is an evaluation of a care procedure to limit the incidence of alveolar derecruitment in ventilated intubated ICU patients during transport for CT scan.

Intra hospital transport of ICU patients are performed by anesthesiologist nurses, the physician entrusts them this activity.

This is a randomized controlled study, the procedure is to clamp endotracheal tube before each disconnection from ventilator.

Enrollment: 250 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• intensive care patient
• intubated, sedated, controlled assisted ventilation
• Intra hospital transport for CT scan
• arterial catheter
• the patient or his trusted person consent to the study

Exclusion criteria

• Patient Covid tests positive or Covid test results not received
• extubated, unsedated,
• reinforced tube
• tracheotomy
• pregnancy
• guardianship

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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250 participants in 2 patient groups

Control group

No Intervention group

Description:

The transport will be released without a clamping of endotracheal tube before each disconnection from ventilator.

Clamping group

Experimental group

Description:

The transport will be released with a clamping of endotracheal tube before each disconnection from ventilator.

Treatment:

Procedure: Clamping of the ventilator endotracheal tube