Triamcinolone Paste to Reduce the Incidence of Postoperative Sore Throat

Soon Chun Hyang University

Status: Completed

Conditions: Tracheal Intubation

Treatments: Drug: chlorhexidine gluconate; Drug: triamcinolone acetonide

Study type: Interventional

Funder types: Other

Identifiers

NCT00908817

ST

Details and patient eligibility

About

The purpose of this study is to determine whether triamcinolone paste applied over tracheal tube is effective to reduce the incidence of postoperative sore throat after tracheal intubation.

Full description

Sore throat is a common postoperative complaint after tracheal intubation. When the surgical pain is well controlled, sore throat is often the predominant complaint, therefore it is important to prevent sore throat.

Enrollment: 150 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA physical status I-II, aged between 20 and 70 years
• scheduled for elective laparoscopic cholecystectomy under general anesthesia with endotracheal intubation

Exclusion criteria

• recent respiratory tract infection or sore throat
• who were using analgesics or steroid preoperatively
• who have risk factors for oral cavity infection
• the surgical duration < 60 minutes or > 300 minutes

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

---

150 participants in 2 patient groups, including a placebo group

triamcinolone

Active Comparator group

Treatment:

Drug: triamcinolone acetonide

chlorhexidine

Placebo Comparator group

Treatment:

Drug: chlorhexidine gluconate