Trigeminal Neuralgia Electrophysiology

University of Minnesota (UMN)

Status: Enrolling

Conditions: Trigeminal Neuralgia

Treatments: Procedure: Trigeminal Electrophysiology

Study type: Observational

Funder types: Other

Identifiers

NCT05269472

NSU-2022-30582

Details and patient eligibility

About

The study intervention is to perform standard somatosensory evoked responses limited to the face during rhizotomy procedures of the gasserian ganglion (trigeminal ganglion) for the treatment of trigeminal neuralgia. The evoked responses will be measured at two locations before and after the clinical rhizotomy including: the standard contralateral scalp (EEG) and at the gasserian ganglion through an FDA-approved recording electrode.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria (TGN):

• Adults of 18 years or older
• Scheduled to undergo percutaneous rhizotomy for facial pain

Exclusion Criteria (TGN):

• Facial pain of unclear origin (i.e. not clearly TGN pain)
• Rhizotomy procedure canceled

Inclusion Criteria (Healthy controls)

• Adults of 18 years or older

Exclusion Criteria (Healthy Controls)

• Diagnosis or history of facial pain such as TMD or TGN
• History of migraine
• History of any functional pain disorder: fibromyalgia, IBS, CRPS
• Recent chronic pain (within last month)
• Unwilling to participate for two hours in lab
• Current acute pain

Trial design

30 participants in 2 patient groups

Trigeminal Electrophysiology

Treatment:

Procedure: Trigeminal Electrophysiology

Controls