Trigeminus-evoked Somatosensory Potentials in Patients Undergoing Carotid Surgery (TRISEP)

Klinikum St. Georg gGmbH

Status: Completed

Conditions: Carotid Surgery

Treatments: Procedure: neuropsychological tests; Procedure: TRI-SEP; Procedure: MED-SEP

Study type: Observational

Funder types: Other

Identifiers

NCT00484796

ISRCTN47041942

Details and patient eligibility

About

Hypothesis: Trigeminus-evoked somatosensory potentials (TRI-SEP) may be used as an alternative technique to medianus-evoked somatosensory potentials (MED-SEP) in patients undergoing elective carotid surgery.

Full description

For CNS-monitoring somatosensory-evoked responses ba electrical stimulation of the contralateral median nerve are established: A reduction of amplitude and a delay in latency may represent a sensible marker of imminent cerebral ischemia. This study will evaluate a new concept by using trigeminal nerve evoked somatosensory evoked potentials in comparison to the established MED-SEP. Beside the comparison of two methods of neuromonitoring, this study will investigate the neurological long-term outcome (90-day evaluation) with different neuropsychological tests for the detection of cognitive deficits.

Enrollment: 120 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age >= 18 years
• Agreement with study procedure
• Elective carotid surgery

Exclusion criteria

• Inability to take somatosensory potentials
• Inability to respond to neuropsychological tests
• Severe preoperative neurological deficit

Trial design

120 participants in 1 patient group

1

Description:

Patients undergoing carotid surgery

Treatment:

Procedure: MED-SEP

Procedure: neuropsychological tests

Procedure: TRI-SEP