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Triglyceride/High-density Lipoprotein Cholesterol Ratio in Chronic Kidney Disease

G

Gulhane School of Medicine

Status

Completed

Conditions

Chronic Kidney Disease

Study type

Observational

Funder types

Other

Identifiers

NCT02113462
GSM-012014

Details and patient eligibility

About

The Triglycerides (TG) to High Density Lipoprotein Cholesterol (HDL-C) ratio is a feature of insulin resistance and an independent predictor of cardiovascular risk. The investigators aimed to evaluate the relationship between TG/HDL-C ratio and the endothelial functions in patients with CKD.

Full description

Cardiovascular disease (CVD) risk is substantially increased in subjects with chronic kidney disease (CKD).The reasons for the elevated risk of CVD in patients with CKD are not fully elucidated. There is not a good prognostic tool for the prediction of increased cardiovascular risk in CKD. A simple, widely available, relatively inexpensive, and generally reproducible marker to predict the CVD risk in subjects with CKD is needed.

The Triglycerides (TG) to High Density Lipoprotein Cholesterol (HDL-C) ratio is a feature of insulin resistance and an independent predictor of cardiovascular risk. No study has been performed so far, to evaluate the role of TG/HDL ratio to predict the CVD risk in patients with CKD.

This study is designed to evaluate the relationship between TG/HDL-C ratio and the endothelial functions in patients with CKD.

Enrollment

197 patients

Sex

All

Ages

20 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patients with chronic kidney disease

Exclusion criteria

  • taking drugs that may influence endothelial function
  • acute infections

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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