TRIM: Danish Form and Dose Study on Vitamin B12

University of Aarhus

Status: Completed

Conditions: Healthy

Treatments: Dietary Supplement: Vitamin B12

Study type: Interventional

Funder types: Other

Identifiers

NCT02832726

KBA B48 2013

Details and patient eligibility

About

The study investigates the absorption of different doses of hydroxocobalamin and cyanocobalamin in a vitamin B12-replete Danish population.

Enrollment: 45 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• At least 18 years old

Exclusion criteria

• Use of vitamin pills with vitamin B12 within the last two weeks of the study
• Treatment with vitamin B12 injections within the last year
• Known chronic systemic disease
• Not able to give informed consent.

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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45 participants in 2 patient groups

cyano-hydroxo B12

Active Comparator group

Description:

Absorption of 3 doses of 9 ug cyano-B12 and 9 ug hydroxo-B12 for two days (the CobaSorb test). No drugs given.

Treatment:

Dietary Supplement: Vitamin B12

Cyano-B12 doses

Active Comparator group

Description:

Absorption of 3 doses of 3 ug, 6 ug, and 9 ug cyano-B12 for two days (the CobaSorb test). No drugs given.

Treatment:

Dietary Supplement: Vitamin B12