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Trunk Control, Balance, Gait, Functional Mobility and Fear of Falling in People With Alzheimer's Disease

A

Ankara Yildirim Beyazıt University

Status

Completed

Conditions

Physical Therapy

Treatments

Other: Functional mobility
Other: Gait
Other: Balance
Other: Trunk control
Other: Fear of falling

Study type

Interventional

Funder types

Other

Identifiers

NCT05576688
2022/30/09

Details and patient eligibility

About

The purposes of this study were to investigate the relationship between trunk control and balance, gait, functional mobility, and fear of falling in people with Alzheimer's disease and to compare trunk control, balance, gait, functional mobility, and fear of falling in people with Alzheimer's disease and healthy older adults.

Balance, an essential motor skill necessary to perform both static and dynamic everyday activities with stability and security, is impaired in people with Alzheimer's disease when compared to cognitively preserved elderlies. Gait and functional mobility disorders are also observed in people with Alzheimer's disease from the early period of the disease. People with Alzheimer's disease tend to fall more often and are more seriously injured from falls than cognitively intact older adults. The annual incidence rate for falling is 60% to 80% for older adults with Alzheimer's disease, over twice the incidence of age-matched cognitively intact older adults.

Trunk control is shown among the most important factors that ensure the balance and walking of the individual in different environments and conditions during functional activities. Optimal trunk control relies on adequate somatosensory, motor, and musculoskeletal systems, which are frequently compromised in people with Alzheimer's disease. For this reason, the investigators think that trunk control may be affected in people with Alzheimer's disease compared to healthy older adults and may be related to balance, gait, functional mobility and fear of falling.

Full description

The study was carried out with the purpose of investigating the relationship between trunk control and balance, gait, functional mobility, and fear of falling in people with Alzheimer's disease and comparing trunk control, balance, gait, functional mobility, and fear of falling in people with Alzheimer's disease and healthy older adults.

35 people with Alzheimer's disease and 33 healthy older adults with matching ages and genders were included the study. Trunk control with Trunk Impairment Scale; balance with Berg Balance Scale, Functional Reach Test, One-Leg Standing Test and Five-Repeat Sit-and-Stand Test; gait with Dynamic Gait Index; functional mobility with Timed Up and Go Test; fear of falling with Falls Efficacy Scale-International were evaluated.

Enrollment

68 patients

Sex

All

Ages

40 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

  • Clinical diagnosis of Alzheimer's disease according to the NINCDS/ARDRA diagnostic criteria by a neurologist.
  • Having a cognitive level between 18-23 points according to the Mini Mental Status Examination.
  • Must be able to walk independently with and/or without assistive device.

Exclusion Criteria

  • Having a history of cerebrovascular disease, epilepsy and brain tumor.
  • Having a cognitive level below 18 points according to the Mini Mental Status Examination.

Trial design

Primary purpose

Screening

Allocation

Non-Randomized

Interventional model

Factorial Assignment

Masking

None (Open label)

68 participants in 2 patient groups

Alzheimer's disease
Experimental group
Description:
People with Alzheimer's disease who were diagnosed with Alzheimer's disease according to NINCDS/ARDRA diagnostic criteria by a neurologist and whose cognitive level was between 18-23 points according to Mini Mental State Examination.
Treatment:
Other: Fear of falling
Other: Trunk control
Other: Functional mobility
Other: Gait
Other: Balance
Healthy older adults
No Intervention group
Description:
33 healthy older adults with matching ages and gender.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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