Tumor Deposits in Colorectal Cancer and Its Prognostic Value in Survival and Metastasis

Minia University

Status: Enrolling

Conditions: Survival; Tumor Deposits; Metastasis; Prognosis; Colorectal Cancer

Treatments: Procedure: Therapeutic resection

Study type: Observational

Funder types: Other

Identifiers

NCT06884839

1267/09/2024

Details and patient eligibility

About

This study aims to evaluate the tumor deposits in colorectal cancer and its prognostic value in survival and metastasis

Full description

Tumor deposits (TDs) are defined as isolated tumor foci found in the pericolonic or perirectal fat or the adjacent mesentery (mesocolonic fat) away from the invasive margin of the tumor without evidence of residual lymphatic tissue. TDs are significantly correlated with poor prognosis after colorectal cancer surgery.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age above 18 years old.
• Both sexes.
• All Colorectal cancer patients From Stage I to III Colorectal cancer with pathologically positive Tumor deposits.

Exclusion criteria

• Patient took neoadjuvant therapy.
• No information available on tumor deposits.
• Colorectal cancer is not the only primary cancer.
• Patients with incomplete information about follow-up.

Trial design

30 participants in 1 patient group

Therapeutic resection group

Description:

Patients with colorectal cancer underwent therapeutic resection with pathologically positive tumor deposits (TDs) to determine distant metastasis occurrence and the effect of TDs on survival.

Treatment:

Procedure: Therapeutic resection