Tumor Growth Factors in Hepatocellular Carcinoma

Kaohsiung Medical University

Status: Completed

Conditions: Hepatocellular Carcinoma

Treatments: Biological: tumor growth factor concentration

Study type: Observational

Funder types: Other

Identifiers

NCT00764140

KMUH-IRB-960010

Details and patient eligibility

About

Malignant cells frequently produce many tumor growth factors to autocidal or endocrinal proliferate growth, metastasis,or angiogenesis about tumor cells. By studying tumor growth factors in hepatocellular carcinoma, one may know the tumor behavior, its relationship with clinical manifestation or invasion, and could be used as diagnostic or prognostic tools.This study aims to study the relationship between tumor growth factors in HCC ant its clinical relevance.

Full description

The clinical relevance of patients will be evaluated by the concentrations of tumor growth factors.

Enrollment: 400 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Histology proven HCC

Exclusion criteria

• No definitely diagnosed tumor

Trial design

400 participants in 2 patient groups

2

Description:

Specific tumor growth factors (IGFs, its binding proteins,receptors; transforming growth factor alpha and beta 1 and epidermal growth factor) in the urine and serum will be measured in patients with hepatocellular carcinoma and healthy controls

1

Description:

Patients with hepatocellular carcinoma and Healthy controls

Treatment:

Biological: tumor growth factor concentration